Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 17/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063247 | 0.87 | DRD2 (0.46) | GPR6MAP3K14HTR6 | |
| SCHEMBL30062832 | 0.79 | GPR119 (0.51) | GPR6 | |
| Tert-Butyl Formate SCHEMBL28042680 | 0.78 | DRD2 (0.40) | HTR6 | |
| Tert-Butyl Formate SCHEMBL28301315 | 0.78 | DRD2 (0.40) | HTR6 | |
| SCHEMBL28301334 | 0.77 | GPR6 (0.44) | GPR6 | |
| SCHEMBL30062506 | 0.76 | BPTF (0.50) | GPR6HTR6 | |
| SCHEMBL30063478 | 0.75 | SYK (0.50) | — | |
| Tert-Butyl Formate SCHEMBL28042674 | 0.74 | HTR1A (0.54) | HTR6 | |
| SCHEMBL30062511 | 0.74 | CTSK (0.48) | GPR6HTR6 | |
| SCHEMBL30061008 | 0.74 | ROCK2 (0.45) | GPR6MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912514-A | (2- heteroaryl aminocarbonyl phenyl) azepine ring derivatives and application thereof | 广东东阳光药业有限公司 | 2019-06-21 | — | — | CN | disclosed |