Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28301315 | 0.86 | DRD2 (0.40) | DRD2DRD3HTR6HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28265602 | 0.81 | HTR6 (0.38) | DRD2DRD3HTR6HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28042829 | 0.81 | ADRB2 (0.44) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27615989 | 0.80 | DRD2 (0.46) | DRD2DRD3HTR3EHTR3BHTR3A | |
| Tert-Butyl Formate SCHEMBL27974539 | 0.80 | ADRB1 (0.47) | DRD2DRD3HTR6HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28267032 | 0.79 | HTR1A (0.44) | HTR6HTR3AHTR2AHTR2C | |
| Tert-Butyl Formate SCHEMBL28265599 | 0.79 | HTR1A (0.51) | HTR6HTR3AHTR2AHTR2C | |
| Tert-Butyl Formate SCHEMBL28301337 | 0.78 | GPR6 (0.39) | HTR6 | |
| Tert-Butyl Formate SCHEMBL28265724 | 0.78 | HTR1A (0.50) | HTR3A | |
| Tert-Butyl Formate SCHEMBL27588079 | 0.76 | HTR5A (0.41) | HTR6HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105294554-A | Phenylpiperazine derivative, use method and uses thereof | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG DRUG TRADING CO LTD | 2016-02-03 | — | — | CN | disclosed |