Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307339 | 0.77 | MAPT (0.38) | KMT2AMAPTATMXBP1MEN1 | |
| SCHEMBL26698357 | 0.77 | KMT2A (0.38) | KMT2ACCNA2CDK2CCNA1MAPT | |
| SCHEMBL28307341 | 0.75 | HTT (0.45) | HRH4MAPTATML3MBTL1LMNA | |
| SCHEMBL28307340 | 0.74 | MAPT (0.39) | KMT2AHRH4MAPTATMMEN1 | |
| SCHEMBL28307335 | 0.71 | HTT (0.38) | HRH4MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28306200 | 0.69 | GLP1R (0.33) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL28307334 | 0.69 | TLR8 (0.37) | KMT2AMAPTL3MBTL1MEN1LMNA | |
| SCHEMBL22696605 | 0.68 | HTT (0.44) | KMT2ACCNA2CDK2CCNA1MAPT | |
| SCHEMBL29974026 | 0.64 | CCNA2 (0.48) | KMT2ACCNA2CDK2CCNA1ATM | |
| SCHEMBL28877937 | 0.64 | CCNA2 (0.48) | KMT2ACCNA2CDK2CCNA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |