Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306200 | 0.86 | GLP1R (0.33) | MAPTMEN1KMT2ASMN1; SMN2NPY1R | |
| SCHEMBL28306176 | 0.83 | KMT2A (0.37) | MAPTMEN1KMT2ASMN1; SMN2NPY1R | |
| SCHEMBL28306191 | 0.83 | MAPT (0.33) | MAPTMEN1KMT2ATDP1GLP1R | |
| SCHEMBL28307339 | 0.80 | MAPT (0.38) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28307341 | 0.77 | HTT (0.45) | MAPTSMN1; SMN2NPY1RTDP1LMNA | |
| SCHEMBL28306205 | 0.74 | KMT2A (0.35) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28307335 | 0.74 | HTT (0.38) | MAPTSMN1; SMN2NPY1RTDP1GLP1R | |
| SCHEMBL28307334 | 0.71 | TLR8 (0.37) | MAPTMEN1KMT2ASMN1; SMN2NPY1R | |
| SCHEMBL28247251 | 0.68 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2NPY1R | |
| SCHEMBL21625495 | 0.67 | PDK1 (0.34) | MAPTMEN1KMT2ASMN1; SMN2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |