Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307334 | 0.92 | TLR8 (0.37) | HTTPOLBNPY1RSMN1; SMN2GAA | |
| SCHEMBL28307341 | 0.90 | HTT (0.45) | HTTPOLBHRH4NPY1RSMN1; SMN2 | |
| SCHEMBL28306175 | 0.83 | MAPT (0.43) | HTTPOLBSMN1; SMN2TDP1MGMT | |
| SCHEMBL28307339 | 0.77 | MAPT (0.38) | HTTSMN1; SMN2GAATDP1LMNA | |
| SCHEMBL28946189 | 0.77 | HTT (0.35) | HTTPOLBPIM3SMN1; SMN2GAA | |
| SCHEMBL28307340 | 0.74 | MAPT (0.39) | HTTPOLBHRH4NPY1RSMN1; SMN2 | |
| SCHEMBL28306191 | 0.72 | MAPT (0.33) | HTTPOLBTDP1KDM4EGLP1R | |
| SCHEMBL28306205 | 0.71 | KMT2A (0.35) | HTTHRH4SMN1; SMN2LMNAMAPT | |
| SCHEMBL8558130 | 0.70 | NOS2 (0.44) | HTTNPY1RSMN1; SMN2KDM4EMGMT | |
| SCHEMBL28306200 | 0.69 | GLP1R (0.33) | HTTNPY1RSMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |