Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | MGMT | P16455 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307340 | 0.86 | MAPT (0.39) | GLP1RMAPTTDP1NPSR1NPY1R | |
| SCHEMBL28306191 | 0.86 | MAPT (0.33) | GLP1RMAPTTDP1KDM4EMAPK1 | |
| SCHEMBL28306176 | 0.78 | KMT2A (0.37) | MAPTTDP1MAPK1NPSR1NPY1R | |
| SCHEMBL28307339 | 0.75 | MAPT (0.38) | MAPTTDP1MAPK1MEN1CYP3A4 | |
| SCHEMBL28307341 | 0.73 | HTT (0.45) | MAPTTDP1NPY1RSMN1; SMN2MGMT | |
| SCHEMBL28306205 | 0.69 | KMT2A (0.35) | MAPTMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL28307335 | 0.69 | HTT (0.38) | GLP1RMAPTTDP1KDM4ENPY1R | |
| SCHEMBL28307334 | 0.68 | TLR8 (0.37) | MAPTTDP1TXNRD1NPSR1NPY1R | |
| SCHEMBL24156059 | 0.62 | LMNA (0.36) | SMN1; SMN2LMNA | |
| SCHEMBL24156659 | 0.62 | GLP1R (0.33) | GLP1RSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |