Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667314 | 0.86 | CALM1 (0.54) | ALOX15MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL3924901 | 0.81 | CA2 (0.66) | ALOX15MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL23637638 | 0.78 | RAB9A (0.50) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2751117 | 0.78 | L3MBTL1 (0.59) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL5606608 | 0.78 | ALOX15 (0.61) | ALOX15MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5109870 | 0.78 | L3MBTL1 (0.48) | ALOX15MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2751487 | 0.77 | ABCB1 (0.60) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2095593 | 0.76 | CA2 (1.00) | ALOX15CYP1A2CYP2C19CA2ACHE | |
| SCHEMBL10623955 | 0.76 | ALOX15 (0.52) | ALOX15MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5115003 | 0.76 | L3MBTL1 (0.49) | ALOX15MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |