Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.47 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.47 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.47 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | ATIC | P31939 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453258 | 0.79 | CYP1A2 (0.67) | MPLALDH1A1HIF1ASENP2SUMO2 | |
| SCHEMBL23787780 | 0.75 | PHLPP2 (0.67) | MPLALDH1A1HTTSENP2SUMO2 | |
| SCHEMBL14159448 | 0.73 | SENP2 (0.78) | MPLALDH1A1HIF1ASENP2SUMO2 | |
| SCHEMBL7538465 | 0.72 | MPL (0.58) | MPLALDH1A1SENP2SUMO2SUMO1 | |
| SCHEMBL3491757 | 0.72 | ALDH1A1 (0.52) | MPLALDH1A1HIF1AHTTSENP2 | |
| SCHEMBL6126114 | 0.72 | BRD4 (0.62) | MPLALDH1A1HIF1ASENP2SUMO2 | |
| SCHEMBL692673 | 0.72 | BRD4 (0.62) | MPLALDH1A1HIF1ASENP2SUMO2 | |
| SCHEMBL1136824 | 0.72 | BRD4 (0.62) | MPLALDH1A1HIF1ASENP2SUMO2 | |
| SCHEMBL14188878 | 0.71 | MEN1 (0.83) | MPLALDH1A1HIF1AHTTSENP2 | |
| SCHEMBL13460242 | 0.71 | LMNA (0.55) | MPLALDH1A1HTTSENP2SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1977729-B1 | Cosmetic compositions containing pearlescent pigments | ECKART GMBH (DE) | 2010-03-03 | — | — | EP | disclosed |
| EP-1635771-A2 | COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004091567-A2 | COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS | MERCK PATENT GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |