SCHEMBL1136824

SCHEMBL1136824

Cc1cc(C)c(S(=O)(=O)O)cc1/N=N/c1cc(S(=O)(=O)O)c2ccccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 2/20 0.62
▸ SENP2 Q9HC62 5/20 0.56
▸ SENP1 Q9P0U3 4/20 0.56
▸ SUMO2 P61956 4/20 0.56
▸ SUMO1 P63165 4/20 0.56
▸ SENP7 Q9BQF6 4/20 0.56
▸ SENP3 Q9H4L4 2/20 0.56
▸ TP53 P04637 1/20 0.54
▸ CREBBP Q92793 1/20 0.54
▸ CYP1A2 P05177 2/20 0.53
▸ PHLPP2 Q6ZVD8 1/20 0.53
▸ THRB P10828 2/20 0.52
▸ APP P05067 2/20 0.52
▸ MAPT P10636 2/20 0.52
▸ SNCA P37840 2/20 0.52
▸ MPL P40238 3/20 0.50
▸ HPGD P15428 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692673 1.00 BRD4 (0.62) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL6126114 1.00 BRD4 (0.62) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL185165 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL4811412 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL185164 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL3188346 0.91 THRB (0.67) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL4841813 0.91 THRB (0.67) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL21433094 0.87 BRD4 (0.54) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL23787780 0.86 PHLPP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL31222680 0.85 CTRB1 (0.66) BRD4SENP2SENP1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976385-A2 Dyestuff for hair and fibers Wella Aktiengesellschaft (DE) 2000-02-02 — — EP claimed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 — — US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 — — US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 — — US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 — — US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 — — US disclosed
US-20070218206-A1 Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate CIBA SPECIALTY CHEMICALS CORP. 2007-09-20 — — US disclosed
US-20070218206-A1 Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate CIBA SPECIALTY CHEMICALS CORP. 2007-09-20 — — US disclosed
EP-1697006-A1 USE OF PEPTIDES TO PROTECT SKIN FROM HAIR TREATMENT AGENTS Wella Aktiengesellschaft (DE) 2006-09-06 — — EP disclosed
US-20060174423-A1 Highly affine cosmetic agent Wella GmbH (DE) 2006-08-10 — — US disclosed
US-20050198746-A1 Leave-in color conditioner HAIRMARKER LLC 2005-09-15 — — US disclosed
WO-2005060929-A1 USE OF PEPTIDES TO PROTECT SKIN FROM HAIR TREATMENT AGENTS WELLA AG (DE) 2005-07-07 — — WO disclosed
EP-1513489-A2 HIGHLY AFFINE COSMETIC AGENT Wella AG (DE) 2005-03-16 — — EP disclosed
WO-2004000257-A2 HIGHLY AFFINE COSMETIC AGENT WELLA AG (DE) 2003-12-31 — — WO disclosed
US-20020000012-A1 Compositions and methods for dyeing keratin fibers, especially hair WELLA AKTIENGESELLSCHAFT (DE) 2002-01-03 — — US disclosed
EP-0976385-A2 Dyestuff for hair and fibers Wella Aktiengesellschaft (DE) 2000-02-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060174423-A1 Highly affine cosmetic agent TYR, ENO1, CUTA BRD4 2730/4885SENP2 975/4885SENP1 997/4885
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 BRD4 1942/4885SENP2 3189/4885SENP1 3483/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 BRD4 1942/4885SENP2 3189/4885SENP1 3483/4885
US-20020000012-A1 Compositions and methods for dyeing keratin fibers, especially hair KRT18, DSG1, KRTCAP2 BRD4 1525/4885SENP2 4092/4885SENP1 4049/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 BRD4 1942/4885SENP2 3189/4885SENP1 3483/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 BRD4 1942/4885SENP2 3189/4885SENP1 3483/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 BRD4 1942/4885SENP2 3189/4885SENP1 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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