SCHEMBL692673

SCHEMBL692673

Cc1cc(C)c(S(=O)(=O)O)cc1N=Nc1cc(S(=O)(=O)O)c2ccccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.62
SENP2 Q9HC62 5/20 0.56
SENP1 Q9P0U3 4/20 0.56
SUMO2 P61956 4/20 0.56
SUMO1 P63165 4/20 0.56
SENP7 Q9BQF6 4/20 0.56
SENP3 Q9H4L4 2/20 0.56
TP53 P04637 1/20 0.54
CREBBP Q92793 1/20 0.54
CYP1A2 P05177 2/20 0.53
PHLPP2 Q6ZVD8 1/20 0.53
THRB P10828 2/20 0.52
APP P05067 2/20 0.52
MAPT P10636 2/20 0.52
SNCA P37840 2/20 0.52
MPL P40238 3/20 0.50
HPGD P15428 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1136824 1.00 BRD4 (0.62) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL6126114 1.00 BRD4 (0.62) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL185165 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL4811412 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL185164 0.99 BRD4 (0.60) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL3188346 0.91 THRB (0.67) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL4841813 0.91 THRB (0.67) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL21433094 0.87 BRD4 (0.54) BRD4SENP2SENP1SUMO2SUMO1
SCHEMBL23787780 0.86 PHLPP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL31222680 0.85 CTRB1 (0.66) BRD4SENP2SENP1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114388077-A Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials 成都市食品药品检验研究院 2022-04-22 CN claimed
US-12133906-B2 Delivery particle THE PROCTER & GAMBLE COMPANY (US) 2024-11-05 US disclosed
US-20220409497-A1 DELIVERY PARTICLE PROCTER & GAMBLE (US) 2022-12-29 US disclosed
CN-114388077-A Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials 成都市食品药品检验研究院 2022-04-22 CN disclosed
EP-3733827-A1 DELIVERY PARTICLES The Procter & Gamble Company (US) 2020-11-04 EP disclosed
US-20200038299-A1 METHODS AND KITS FOR COLORING HAIR NOXELL CORPORATION 2020-02-06 US disclosed
EP-3515561-A1 METHODS AND KITS FOR COLORING HAIR Noxell Corporation (US) 2019-07-31 EP disclosed
EP-2563508-B1 DELIVERY PARTICLE PROCTER & GAMBLE (US) 2019-07-10 EP disclosed
US-20190142714-A1 DELIVERY PARTICLE PROCTER & GAMBLE (US) 2019-05-16 US disclosed
US-20180360706-A1 Delivery Particles PROCTER & GAMBLE (US) 2018-12-20 US disclosed
US-7306632-B2 Leave-in color conditioner HAIRMARKER LLC (US) 2007-12-11 US disclosed
EP-1718601-A1 (3,5-DIAMINOPHENYL)(2,4-DIHYDROXYPHENYL)METHANONE AND ITS ACID ADDUCTS, METHOD FOR THE PRODUCTION OF THE LATTER AND USE OF SAID COMPOUNDS FOR COLOURING FIBRES Wella Aktiengesellschaft (DE) 2006-11-08 EP disclosed
US-20060174423-A1 Highly affine cosmetic agent Wella GmbH (DE) 2006-08-10 US disclosed
EP-1636219-A1 NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS Wella Aktiengesellschaft (DE) 2006-03-22 EP disclosed
US-20050198746-A1 Leave-in color conditioner HAIRMARKER LLC 2005-09-15 US disclosed
WO-2005080315-A1 (3,5-DIAMINOPHENYL)(2,4-DIHYDROXYPHENYL)METHANONE AND ITS ACID ADDUCTS, METHOD FOR THE PRODUCTION OF THE LATTER AND USE OF SAID COMPOUNDS FOR COLOURING FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-09-01 WO disclosed
WO-2004106332-A1 NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2004-12-09 WO disclosed
EP-1313434-A1 OXIDATION DYE Wella Aktiengesellschaft (DE) 2003-05-28 EP disclosed
WO-2002069919-A1 OXIDATION DYE WELLA AKTIENGESELLSCHAFT (DE) 2002-09-12 WO disclosed
US-20020000012-A1 Compositions and methods for dyeing keratin fibers, especially hair WELLA AKTIENGESELLSCHAFT (DE) 2002-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220409497-A1 DELIVERY PARTICLE LIPA, CHMP4B, SLC46A1 BRD4 4406/4885SENP2 1045/4885SENP1 2054/4885
US-20060174423-A1 Highly affine cosmetic agent TYR, ENO1, CUTA BRD4 2730/4885SENP2 975/4885SENP1 997/4885
US-20180360706-A1 Delivery Particles LIPA, CHMP4B, ABCB4 BRD4 4395/4885SENP2 1276/4885SENP1 2329/4885
US-20020000012-A1 Compositions and methods for dyeing keratin fibers, especially hair KRT18, DSG1, KRTCAP2 BRD4 1525/4885SENP2 4092/4885SENP1 4049/4885
US-20200038299-A1 METHODS AND KITS FOR COLORING HAIR ALPG, COXFA4L2, MC1R BRD4 3579/4885SENP2 3804/4885SENP1 3843/4885
US-12133906-B2 Delivery particle LIPA, CHMP4B, SLC46A1 BRD4 4406/4885SENP2 1045/4885SENP1 2054/4885
US-20190142714-A1 DELIVERY PARTICLE LIPA, CHMP4B, SLC46A1 BRD4 4406/4885SENP2 1045/4885SENP1 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.