Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311451 | 0.84 | HSD11B1 (0.61) | HSD11B1SLC22A12GAAKMT2AKDM4E | |
| SCHEMBL4616809 | 0.81 | ABCC9 (0.51) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29058030 | 0.81 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8FEN1 | |
| SCHEMBL29039869 | 0.79 | FFAR4 (0.52) | ABCC9ABCC8KCNJ11KCNJ8FEN1 | |
| SCHEMBL4618522 | 0.78 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8MAOB | |
| SCHEMBL28311437 | 0.78 | HSD11B1 (0.64) | HSD11B1SLC22A12KMT2AALDH1A1HTR6 | |
| SCHEMBL3151230 | 0.78 | MTNR1B (0.56) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL31352975 | 0.78 | MTNR1B (0.56) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL15486381 | 0.77 | SLC22A12 (0.77) | SLC22A12KMT2AALDH1A1CYP3A4HPGD | |
| SCHEMBL14282636 | 0.76 | PGR (0.56) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |