Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352975 | 0.82 | MTNR1B (0.56) | FFAR4ALDH1A1NFE2L2KEAP1HTR6 | |
| SCHEMBL3151230 | 0.82 | MTNR1B (0.56) | FFAR4ALDH1A1NFE2L2KEAP1HTR6 | |
| SCHEMBL8933453 | 0.81 | PKM (0.62) | FFAR4ALDH1A1KEAP1HTR6 | |
| Anisole SCHEMBL11531120 | 0.81 | CA4 (0.54) | FFAR4ALDH1A1KEAP1HTR6PGR | |
| SCHEMBL14282636 | 0.81 | PGR (0.56) | FFAR4NFE2L2KEAP1HTR6PGR | |
| SCHEMBL16495047 | 0.80 | NFE2L2 (0.50) | FFAR4FEN1NFE2L2KEAP1HTR6 | |
| SCHEMBL28311554 | 0.79 | HSD11B1 (0.50) | ALDH1A1FEN1NFE2L2KEAP1HTR6 | |
| SCHEMBL14282635 | 0.77 | HTT (0.59) | FFAR4ALDH1A1NFE2L2HTR6PTGDR2 | |
| SCHEMBL1713160 | 0.77 | HTR6 (0.57) | ALDH1A1HTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL31092469 | 0.77 | HTR6 (0.57) | ALDH1A1HTR6ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496136-A | Diaryl sulfone compound and preparation method thereof | 华北水利水电大学 | 2023-07-28 | — | — | CN | disclosed |