Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057982 | 0.85 | ALDH1A1 (0.46) | HSD11B1KMT2ACNR1POLB | |
| SCHEMBL28312428 | 0.85 | HSD11B1 (0.48) | HSD11B1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL29058002 | 0.83 | HSD11B1 (0.49) | HSD11B1HTR6KMT2AABCC9ABCC8 | |
| SCHEMBL29057974 | 0.83 | ABCC9 (0.44) | HSD11B1HTR6KMT2AABCC9ABCC8 | |
| SCHEMBL30394065 | 0.83 | ABCC9 (0.44) | HSD11B1HTR6KMT2AABCC9ABCC8 | |
| SCHEMBL29057923 | 0.82 | PKM (0.50) | HSD11B1KMT2AGAA | |
| SCHEMBL4617322 | 0.81 | HTR6 (0.44) | HSD11B1HTR6KMT2ATSHRHTT | |
| SCHEMBL28312442 | 0.80 | HSD11B1 (0.49) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL28311452 | 0.80 | CA1 (0.43) | HSD11B1KMT2ACNR1SLC22A12CA1 | |
| SCHEMBL29058030 | 0.79 | ABCC9 (0.47) | HTR6KMT2AABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |