Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312404 | 0.85 | HSD11B1 (0.48) | HSD11B1KMT2AGAACNR1ABCC9 | |
| SCHEMBL30394065 | 0.85 | ABCC9 (0.44) | HSD11B1MEN1KMT2ACNR1ABCC9 | |
| SCHEMBL29057974 | 0.85 | ABCC9 (0.44) | HSD11B1MEN1KMT2ACNR1ABCC9 | |
| SCHEMBL29057982 | 0.84 | ALDH1A1 (0.46) | HSD11B1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL29057923 | 0.84 | PKM (0.50) | HSD11B1KMT2AGAACNR2 | |
| SCHEMBL29057942 | 0.81 | GAA (0.41) | KMT2AGAACNR1CNR2ALDH1A1 | |
| SCHEMBL28312420 | 0.76 | GAA (0.47) | HSD11B1MEN1KMT2AGAACNR1 | |
| SCHEMBL29058002 | 0.76 | HSD11B1 (0.49) | HSD11B1MEN1KMT2ACNR1ABCC9 | |
| SCHEMBL29058030 | 0.76 | ABCC9 (0.47) | KMT2AGAAABCC9ABCC8KCNJ11 | |
| SCHEMBL28311469 | 0.76 | HSD11B1 (0.66) | HSD11B1MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |