Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312438 | 0.85 | HTR6 (0.47) | GAAKMT2AALDH1A1HSD11B1CNR2 | |
| SCHEMBL29058016 | 0.84 | FEN1 (0.44) | KMT2AFEN1HTR2AHTR2CKCNH2 | |
| SCHEMBL30394880 | 0.84 | FEN1 (0.44) | KMT2AFEN1HTR2AHTR2CKCNH2 | |
| SCHEMBL28312417 | 0.84 | FEN1 (0.40) | KMT2AHSD11B1CNR2FEN1HTT | |
| SCHEMBL29058018 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD11B1CNR2 | |
| SCHEMBL29057960 | 0.83 | PKM (0.51) | GAAKMT2AHSD11B1SMN1; SMN2RAPGEF4 | |
| SCHEMBL29057994 | 0.81 | HSD11B1 (0.50) | COMTHSD11B1CNR2CNR1 | |
| SCHEMBL29057990 | 0.80 | GAA (0.41) | GAAKMT2AALDH1A1CNR2POLB | |
| SCHEMBL28312428 | 0.76 | HSD11B1 (0.48) | GAAMEN1KMT2ACOMTALDH1A1 | |
| SCHEMBL16896856 | 0.75 | PTGS2 (0.39) | MEN1KMT2AALDH1A1KCNH2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |