Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606361 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HSD17B10IDO1KDM4E | |
| SCHEMBL434024 | 0.84 | KDM4E (0.34) | ALDH1A1L3MBTL1HSD17B10IDO1KDM4E | |
| SCHEMBL2886283 | 0.81 | — | — | |
| SCHEMBL6242090 | 0.79 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HSD17B10IDO1KDM4E | |
| SCHEMBL28313466 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD17B10IDO1KDM4E | |
| SCHEMBL8129047 | 0.77 | ACHE (0.41) | ALDH1A1HSD17B10KCNN4SMN1; SMN2CYP3A4 | |
| SCHEMBL7822011 | 0.77 | CYP2A6 (0.39) | ALDH1A1KCNN4IDO1SMN1; SMN2NPC1 | |
| SCHEMBL397863 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1HSD17B10KCNN4IDO1 | |
| SCHEMBL28313455 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1HSD17B10IDO1SMN1; SMN2 | |
| SCHEMBL28898295 | 0.75 | NUDT1 (0.36) | ALDH1A1L3MBTL1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177796-A | Novel quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy comprising said quinolinone derivative as active ingredient | 高丽大学校世宗产学协力团 | 2019-08-27 | — | — | CN | disclosed |