Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377001 | 0.85 | HSD11B1 (0.42) | ALDH1A1HSD17B10HSD11B1NOTUMAR | |
| SCHEMBL14483362 | 0.83 | GLA (0.38) | POLBGLAGAATSHR | |
| SCHEMBL2437987 | 0.81 | PDE3B (0.36) | PDK2HSD11B1NOTUMAR | |
| SCHEMBL8124404 | 0.79 | AR (0.44) | HSD11B1AR | |
| SCHEMBL27606361 | 0.79 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1GLAGAATSHR | |
| SCHEMBL397945 | 0.79 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1POLBGLAGAA | |
| SCHEMBL7370399 | 0.77 | KDM4E (0.37) | ALDH1A1POLBGLAGAAHSD17B10 | |
| SCHEMBL1369645 | 0.77 | KIF11 (0.38) | ALDH1A1GLAGAATSHRHSD11B1 | |
| SCHEMBL28313472 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAHSD17B10PDK2 | |
| SCHEMBL2331156 | 0.75 | GLA (0.35) | POLBGLAGAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177796-A | Novel quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy comprising said quinolinone derivative as active ingredient | 高丽大学校世宗产学协力团 | 2019-08-27 | — | — | CN | disclosed |