Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | BRD1 | O95696 | 2/20 | 0.62 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.62 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PKLR | P30613 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316252 | 0.94 | LMNA (0.69) | ATMPGRBRD1BRPF1BRPF3 | |
| SCHEMBL852159 | 0.86 | PRSS1 (0.65) | ATMPGRBRD1BRPF1BRPF3 | |
| SCHEMBL28396503 | 0.82 | PGR (0.77) | ATMPGRBRD1BRPF1LMNA | |
| SCHEMBL29549847 | 0.82 | PGR (0.77) | ATMPGRBRD1BRPF1LMNA | |
| SCHEMBL20021987 | 0.82 | PGR (0.77) | ATMPGRBRD1BRPF1LMNA | |
| SCHEMBL14645822 | 0.81 | CYP19A1 (0.75) | ALDH1A1CYP19A1GAAPKMAR | |
| SCHEMBL7572258 | 0.81 | CYP19A1 (0.75) | PGRALDH1A1CYP19A1PKMAR | |
| SCHEMBL7572129 | 0.80 | GLO1 (0.60) | BRD1BRPF1BRPF3CYP19A1AR | |
| SCHEMBL808105 | 0.80 | ATM (0.72) | ATMPGRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9942088 | 0.80 | ATM (0.72) | ATMPGRLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| US-20140235619-A1 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | NONO INC. (CA) | 2014-08-21 | — | — | US | disclosed |
| US-20140221423-A1 | Agents And Methods For Treating Ischemic And Other Diseases | NONO INC. (CA) | 2014-08-07 | — | — | US | disclosed |
| US-20110251182-A1 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | NONO, INC. (CA) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251182-A1 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | TRPM7, TRPM8, TRPM6 | ATM 1792/4885PGR 4448/4885BRD1 3483/4885 |
| US-20140235619-A1 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | TRPM7, TRPM8, TRPM6 | ATM 1792/4885PGR 4448/4885BRD1 3483/4885 |
| US-20140221423-A1 | Agents And Methods For Treating Ischemic And Other Diseases | TRPM7, TRPM8, TRPM5 | ATM 2475/4885PGR 3698/4885BRD1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.