Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279771 | 0.83 | TSHR (0.48) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL20660752 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL29210715 | 0.81 | PTGDR2 (0.56) | TSHRMGLLALDH1A1POLBLMNA | |
| SCHEMBL28738825 | 0.80 | AAK1 (0.47) | TSHRMGLLALDH1A1POLBLMNA | |
| SCHEMBL28931511 | 0.79 | TSHR (0.47) | TSHRMGLLALDH1A1POLBLMNA | |
| SCHEMBL5929563 | 0.79 | ACHE (0.50) | ALDH1A1POLBLMNASMN1; SMN2KDM4E | |
| SCHEMBL25275004 | 0.77 | L3MBTL1 (0.58) | TSHRPOLBLMNASMN1; SMN2KDM4E | |
| SCHEMBL2569698 | 0.77 | ALDH1A1 (0.48) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL1737797 | 0.76 | CFD (0.53) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL26136337 | 0.75 | MGLL (0.67) | MGLLPOLBSMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |