Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.59 |
| ▸ | FABP3 | P05413 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020733 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL4559831 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL3794261 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL4559828 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL3682579 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL3794524 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL4559570 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL4559573 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL1151027 | 0.83 | EP300 (0.69) | EP300PPARGPPARA | |
| SCHEMBL2020730 | 0.83 | EP300 (0.69) | EP300PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612161-B | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110612161-A | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2019-12-24 | — | — | CN | disclosed |