Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416585 | 0.86 | TP53 (0.41) | KMT2ATSHRCYP1A2ACHELMNA | |
| Fluoride SCHEMBL27660670 | 0.84 | TP53 (0.39) | KMT2ATSHRCYP1A2ACHELMNA | |
| SCHEMBL28998330 | 0.80 | LMNA (0.43) | KMT2ATSHRCYP2C19TDP1L3MBTL1 | |
| SCHEMBL28341634 | 0.78 | ALDH1A1 (0.42) | KMT2ATSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL24849476 | 0.74 | NFE2L2 (0.44) | NFE2L2TSHRCYP1A2ACHEPLA2G1B | |
| SCHEMBL4464860 | 0.72 | — | — | |
| SCHEMBL25909619 | 0.71 | TAAR1 (0.43) | PLA2G1BATG4BLMNAALDH1A1KDM4E | |
| Fluorobenzene SCHEMBL2006171 | 0.71 | NFE2L2 (0.46) | NFE2L2KMT2ATSHRMAPK1HSD17B10 | |
| Fluorobenzene SCHEMBL27617521 | 0.70 | TP53 (0.45) | NFE2L2KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL28444995 | 0.68 | LMNA (0.43) | KMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235995-B | Chiral dihydrosilane compound and synthesis method and application thereof | 浙江大学 | 2019-12-24 | — | — | CN | disclosed |