Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416585 | 0.88 | TP53 (0.41) | LMNAACHETSHRALOX12MEN1 | |
| Fluoride SCHEMBL27660670 | 0.85 | TP53 (0.39) | LMNAACHETSHRALOX12MEN1 | |
| SCHEMBL28339152 | 0.80 | NFE2L2 (0.37) | LMNAACHETSHRTDP1HTT | |
| SCHEMBL10319853 | 0.80 | LMNA (0.42) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL7825995 | 0.75 | ACHE (0.53) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL2455761 | 0.75 | ACHE (0.53) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL12191027 | 0.73 | ACHE (0.50) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL3481851 | 0.72 | LMNA (0.39) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL25909607 | 0.72 | CYP1A2 (0.43) | LMNAACHETSHRALOX12RAB9A | |
| SCHEMBL3481591 | 0.71 | ACHE (0.48) | LMNAACHETSHRALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920768-A | Preparation method and application of tert-butyl substituted dihydrosilane and chiral silane | 深圳湾实验室 | 2022-08-19 | — | — | CN | disclosed |