Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951391 | 0.82 | HSD11B1 (0.56) | KEAP1NFE2L2ALDH1A1RORCNR1H3 | |
| SCHEMBL7014081 | 0.80 | KEAP1 (0.53) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL10592552 | 0.79 | CA12 (0.53) | KEAP1NFE2L2KDM4ELMNA | |
| SCHEMBL28035458 | 0.78 | HTT (0.63) | MMP3PTGDR2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28141663 | 0.77 | HTR2A (0.50) | KEAP1NFE2L2MMP3TRPV4ALDH1A1 | |
| SCHEMBL28783481 | 0.75 | CA12 (0.57) | ALDH1A1HTTRORCHSD11B1MMP1 | |
| SCHEMBL12550044 | 0.74 | STAT5B (0.49) | KEAP1NFE2L2ALDH1A1BMP1RORC | |
| SCHEMBL13465623 | 0.72 | TRPV4 (0.67) | MMP3TRPV4ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16508752 | 0.71 | HTR2A (0.48) | MMP3TRPV4ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6229257 | 0.70 | MLYCD (0.54) | ALDH1A1SERPINE1HTTNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139851-A | Antitumor compounds | 法马马有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114736219-A | Antitumor compounds | 法马马有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |