Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864732 | 0.98 | L3MBTL1 (0.71) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| Bromide SCHEMBL28652885 | 0.96 | L3MBTL1 (0.69) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL6824194 | 0.94 | KMT2A (0.67) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL13670598 | 0.90 | KDM4E (0.63) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL13443099 | 0.90 | KMT2A (0.67) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL941089 | 0.86 | KMT2A (0.78) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL13472214 | 0.86 | HDAC3 (0.53) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL173470 | 0.85 | KMT2A (0.75) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL13472222 | 0.85 | HDAC1 (0.55) | L3MBTL1TDP1LMNAMAPTKMT2A | |
| SCHEMBL9670891 | 0.84 | GSR (0.58) | KMT2ANPC1RAB9AEGFRGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041781-A1 | PREPARATION OF 3-AMINOALKYL-SUBSTITUTED INDOLE DERIVATIVES FROM PHENYLHYDRAZINES AND AMINOKETONES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-05-21 | — | — | WO | claimed |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-08-29 | — | — | US | disclosed |
| EP-4410772-A2 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | Infineum International Limited (GB) | 2024-08-07 | — | — | EP | disclosed |
| CN-118440229-A | Amine functional monomers and methods of making the same | 英菲诺姆国际有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-20200345661-A1 | SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | disclosed |
| EP-1898909-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2016-10-19 | — | — | EP | disclosed |
| EP-1898909-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2016-10-19 | — | — | EP | disclosed |
| US-8841321-B2 | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-23 | — | — | US | disclosed |
| US-20100048585-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-02-25 | — | — | US | disclosed |
| CN-101252927-A | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-27 | — | — | CN | disclosed |
| CN-101247811-A | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-20 | — | — | CN | disclosed |
| EP-1898909-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1898914-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000435-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007000434-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007000434-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2004041781-A1 | PREPARATION OF 3-AMINOALKYL-SUBSTITUTED INDOLE DERIVATIVES FROM PHENYLHYDRAZINES AND AMINOKETONES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-05-21 | — | — | WO | disclosed |
| US-5068368-A | Reaction of lithium amide with acetylene and reaction with a ketone | CYPRUS FOOTE MINERAL COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048585-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | NQO2, HRH1, HRH2 | L3MBTL1 2013/4885TDP1 3416/4885LMNA 4164/4885 |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | AMD1, HNMT, MAT1A | L3MBTL1 1448/4885TDP1 110/4885LMNA 1866/4885 |
| US-20200345661-A1 | SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE | CMKLR1, CMKLR2, IL1RN | L3MBTL1 2724/4885TDP1 2084/4885LMNA 882/4885 |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | CMKLR1, CMKLR2, IL1RN | L3MBTL1 2724/4885TDP1 2084/4885LMNA 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.