Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397524 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1AKR1C3POLBLMNA | |
| SCHEMBL28345520 | 0.82 | LSS (0.46) | LSSGPR183TP53PTGS2HRH3 | |
| SCHEMBL28396249 | 0.76 | MAPT (0.56) | TP53SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28348405 | 0.76 | HRH4 (0.47) | TP53ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28396620 | 0.75 | POLB (0.48) | SMN1; SMN2ALDH1A1AKR1C3POLBLMNA | |
| SCHEMBL28400986 | 0.73 | HPGD (0.50) | SMN1; SMN2ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL28393540 | 0.73 | KMT2A (0.55) | TP53ALDH1A1POLBLMNAMAPT | |
| SCHEMBL28888486 | 0.72 | L3MBTL1 (0.45) | TP53ALDH1A1KDM4EAKR1C3POLB | |
| SCHEMBL28394262 | 0.72 | L3MBTL1 (0.43) | TP53ALDH1A1KDM4EAKR1C3POLB | |
| SCHEMBL28394808 | 0.72 | GAA (0.51) | SMN1; SMN2ALDH1A1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |