Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345522 | 0.88 | BCL2 (0.42) | ALDH1A1KDM4ELMNATACR3 | |
| SCHEMBL28346207 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMAPTTSHR | |
| SCHEMBL28401171 | 0.83 | LMNA (0.45) | ALDH1A1KDM4ELMNAMAPTTSHR | |
| SCHEMBL28345508 | 0.82 | LSS (0.48) | LSSHRH3GPR183ALDH1A1KDM4E | |
| SCHEMBL28348392 | 0.78 | HRH4 (0.48) | ALDH1A1KDM4ETP53POLBLMNA | |
| SCHEMBL28393000 | 0.76 | ADAMTS5 (0.45) | ALDH1A1LMNAMAPTTSHRHTT | |
| SCHEMBL28364424 | 0.75 | POLB (0.45) | ALDH1A1KDM4ETP53POLBLMNA | |
| SCHEMBL28397526 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TP53POLBLMNAMAPT | |
| SCHEMBL28400024 | 0.74 | LMNA (0.43) | ALDH1A1KDM4ETP53POLBLMNA | |
| SCHEMBL28391828 | 0.73 | KMT2A (0.50) | ALDH1A1KDM4EPOLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |