Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 13/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345520 | 0.88 | LSS (0.46) | TACR3KDM4EALDH1A1LMNA | |
| SCHEMBL28346207 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL28401171 | 0.80 | LMNA (0.45) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL28397526 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL28348392 | 0.75 | HRH4 (0.48) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL28348407 | 0.73 | MAOB (0.47) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL28396618 | 0.72 | SMN1; SMN2 (0.51) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28393000 | 0.72 | ADAMTS5 (0.45) | ALDH1A1SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL28364424 | 0.72 | POLB (0.45) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL1958329 | 0.71 | HTR7 (0.55) | BCL2BAK1HTR7BCL2L1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |