Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7366582 | 0.70 | HRH1 (0.32) | — | |
| SCHEMBL7516513 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4ECES1HPGDCYP2C19 | |
| SCHEMBL6592274 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDALOX12HTT | |
| Hydrochloric Acid SCHEMBL7366583 | 0.66 | — | — | |
| SCHEMBL68563 | 0.64 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL9523612 | 0.64 | CA2 (0.54) | — | |
| SCHEMBL68066 | 0.63 | VHL (0.50) | ALDH1A1KDM4ECES1HPGD | |
| SCHEMBL12471284 | 0.63 | MEN1 (0.47) | ALDH1A1KDM4EHPGDALOX12HTT | |
| SCHEMBL4420836 | 0.63 | S100A4 (0.37) | ALDH1A1KDM4ECES1 | |
| SCHEMBL4255191 | 0.63 | TDP2 (0.36) | ALDH1A1KDM4ECES1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586484-B | Thienopyran carboxamides and their use | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |