Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297682 | 0.84 | AKR1C1 (0.39) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL2835097 | 0.80 | AKR1C1 (0.45) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL5960470 | 0.80 | AKR1C1 (0.45) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL8528509 | 0.74 | AKR1C1 (0.47) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL27835257 | 0.72 | AKR1C1 (0.50) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL27806267 | 0.72 | AKR1C1 (0.45) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL146717 | 0.72 | AKR1C1 (0.45) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL10711205 | 0.72 | AKR1C1 (0.45) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL4375040 | 0.71 | L3MBTL1 (0.47) | MEN1KMT2AAKR1C1ALDH1A1TSHR | |
| SCHEMBL7892823 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2AAKR1C1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110295019-A1 | Method for Producing Hydroxymethyl Diphenyloxiranes and Corresponding 1-azolylmethyl-1,2-diphenyloxiranes | BASF SE (DE) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295019-A1 | Method for Producing Hydroxymethyl Diphenyloxiranes and Corresponding 1-azolylmethyl-1,2-diphenyloxiranes | DHPS, HMOX2, HMOX1 | MEN1 3376/4885KMT2A 572/4885AKR1C1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.