Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686950 | 0.77 | CYP1A2 (0.52) | ALDH1A1HSD17B10ALOX15USP2GLA | |
| SCHEMBL2578134 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ALOX15USP2GLA | |
| SCHEMBL6945643 | 0.71 | HPGD (0.46) | ALDH1A1ALOX15KDM4EGLALMNA | |
| SCHEMBL960185 | 0.70 | LTB4R (0.49) | ALDH1A1KDM4EGLALMNAMEN1 | |
| SCHEMBL1449520 | 0.70 | HTT (0.65) | ALDH1A1ALOX15KDM4EGLAHPGD | |
| SCHEMBL11010902 | 0.69 | MAOA (0.45) | ALDH1A1GLALMNARAB9ASMN1; SMN2 | |
| SCHEMBL15971904 | 0.68 | MEN1 (0.44) | ALDH1A1ALOX15KDM4EGLALMNA | |
| SCHEMBL11636011 | 0.66 | KDM4E (0.55) | ALDH1A1ALOX15KDM4EGLALMNA | |
| SCHEMBL7484753 | 0.66 | MPO (0.46) | ALDH1A1KDM4ELMNARAB9AMEN1 | |
| SCHEMBL10986706 | 0.66 | CTNNB1 (0.44) | ALDH1A1HSD17B10ALOX15KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110679602-B | Application of alkaloid esramycin and derivatives thereof in resisting plant viruses | 河北工业大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-110679602-A | Application of alkaloid esramycin and derivatives thereof in resisting plant viruses | 河北工业大学 | 2020-01-14 | — | — | CN | disclosed |