Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960185 | 0.83 | LTB4R (0.49) | GAALMNAGLAGFERMPO | |
| SCHEMBL17279708 | 0.79 | ALPL (0.53) | LMNARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7484753 | 0.74 | MPO (0.46) | MAOAGAALMNAGFERRAB9A | |
| SCHEMBL16341398 | 0.74 | GRIN2B (0.57) | LMNAGLAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30939057 | 0.74 | ALPL (0.44) | LMNARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8656235 | 0.73 | CASP1 (0.44) | GAALMNAGFERALDH1A1MAPT | |
| SCHEMBL17279768 | 0.73 | ADORA3 (0.45) | RAB9AALDH1A1MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL16231996 | 0.73 | DAO (0.51) | RAB9ASMN1; SMN2NPC1DAO | |
| SCHEMBL11603796 | 0.71 | RAB9A (0.59) | MAOAMAOBGAAGFERRAB9A | |
| SCHEMBL7659167 | 0.71 | PARP1 (0.46) | RAB9ANPC1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536508-A | ANTIALLERGENS AND ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1985-08-20 | — | — | US | disclosed |
| EP-0016565-B1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| EP-0016565-A1 | 1,2,4-Triazole derivatives, processes for their production and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1980-10-01 | — | — | EP | disclosed |