Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357291 | 0.84 | MAPT (0.30) | MAPTCASP1CASP7 | |
| SCHEMBL28357608 | 0.79 | — | — | |
| SCHEMBL28357607 | 0.79 | HTR6 (0.39) | — | |
| SCHEMBL17926097 | 0.77 | HDAC1 (0.32) | — | |
| SCHEMBL17926095 | 0.77 | HDAC1 (0.32) | — | |
| SCHEMBL28357280 | 0.74 | CCR5 (0.31) | — | |
| SCHEMBL17926361 | 0.72 | MAPT (0.36) | MAPTCASP1CASP7 | |
| SCHEMBL17925575 | 0.70 | ALDH1A1 (0.37) | MAPTCASP1CASP7 | |
| SCHEMBL28357473 | 0.69 | MEN1 (0.39) | MAPT | |
| SCHEMBL19786570 | 0.68 | MEN1 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804061-B | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2021-01-05 | — | — | CN | disclosed |
| CN-110804061-A | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2020-02-18 | — | — | CN | disclosed |