Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360755 | 0.87 | CA9 (0.49) | ALDH1A1HPGDUSP2CA9AKR1B1 | |
| SCHEMBL28756601 | 0.86 | TUBB4A (0.47) | ALDH1A1HPGDCA9AKR1B1TUBB4A | |
| SCHEMBL28360775 | 0.84 | HSD11B1 (0.50) | ALDH1A1HPGDUSP2CA9AKR1B1 | |
| SCHEMBL28356945 | 0.84 | CA9 (0.53) | ALDH1A1HPGDUSP2CA9AKR1B1 | |
| SCHEMBL28360812 | 0.84 | NPC1 (0.53) | USP2CA9AKR1B1CA12ALDH2 | |
| SCHEMBL28360763 | 0.83 | TXNRD1 (0.40) | ALDH1A1HPGDCA9AKR1B1TUBB4A | |
| SCHEMBL28357051 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HPGDUSP2CA9AKR1B1 | |
| SCHEMBL28356929 | 0.80 | KMT2A (0.49) | ALDH1A1HPGDUSP2CA9AKR1B1 | |
| SCHEMBL28356950 | 0.79 | TUBB4A (0.54) | ALDH1A1HPGDCA9TUBB4ATUBB | |
| SCHEMBL28360752 | 0.78 | NFE2L2 (0.53) | ALDH1A1HPGDTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928176-B | Coumarin-containing 1, 4-pentadiene-3-ketone derivative and preparation method and application thereof | 贵州大学 | 2020-02-18 | — | — | CN | disclosed |