SCHEMBL2836274

SCHEMBL2836274

c1ccc(Nc2nnn[nH]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
TAAR1 Q96RJ0 1/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 3/20 0.44
MAPT P10636 5/20 0.43
GAA P10253 4/20 0.43
METAP2 P50579 4/20 0.43
GFER P55789 3/20 0.43
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 3/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
MAPK1 P28482 1/20 0.42
PTGS2 P35354 1/20 0.42
HTR2B P41595 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27778339 0.98 MEN1 (0.44) MEN1KMT2ATAAR1LMNAHSD17B10
SCHEMBL9203352 0.78 MEN1 (0.50) MEN1KMT2ALMNAMAPTGAA
SCHEMBL1239469 0.77
SCHEMBL13715672 0.74 SMN1; SMN2 (0.57) MEN1KMT2ATAAR1MAPTTSHR
SCHEMBL5185274 0.74
SCHEMBL5369831 0.73 KMT2A (0.46) MEN1KMT2ALMNAMAPTMETAP2
SCHEMBL8824766 0.72 ROCK1 (0.50) MEN1KMT2ALMNAMAPTGAA
Biphenyl SCHEMBL28349298 0.72 XDH (0.40) ALDH1A1TDP1TSHRMAPK1L3MBTL1
SCHEMBL6632277 0.71 SMN1; SMN2 (0.49) MEN1KMT2ALMNAHSD17B10GAA
SCHEMBL11293292 0.71 MAPT (0.30) HSD17B10MAPTSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3686207-B1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2024-10-23 EP claimed
CN-101248054-B Thiazole derivatives and use thereof MERCK SERONO SA 2012-05-09 CN claimed
US-20070102076-A1 Gas-producing mixtures DELPHI TECHNOLOGIES, INC. (US) 2007-05-10 US claimed
EP-0809616-A1 GAS-GENERATING MIXTURES Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) 1997-12-03 EP claimed
WO-1996026169-A1 GAS-GENERATING MIXTURES DYNAMIT NOBEL GMBH (DE) 1996-08-29 WO claimed
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
US-20240368131-A1 OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF VENTUS THERAPEUTICS U S INC (US) 2024-11-07 US disclosed
EP-3686207-B1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2024-10-23 EP disclosed
CN-116183591-A Gold nanoparticle for detecting cadmium ions and preparation method and application thereof 宁波大学 2023-05-30 CN disclosed
CN-111108111-B Tetrazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2023-05-02 CN disclosed
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2022-10-18 US disclosed
EP-0809616-A1 GAS-GENERATING MIXTURES Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) 1997-12-03 EP disclosed
WO-1996026169-A1 GAS-GENERATING MIXTURES DYNAMIT NOBEL GMBH (DE) 1996-08-29 WO disclosed
WO-1995014679-A1 TETRAZOLE-SUBSTITUTED UREA ACAT INHIBITORS PARKE, DAVIS & COMPANY (US) 1995-06-01 WO disclosed
EP-0413051-B1 Benzothiazine-1,1-dioxide derivatives NIPPON HYPOX LAB INC (JP) 1995-03-15 EP disclosed
US-5362744-A Treatnent of athrosclerosis, anticholesterol agents WARNER-LAMBERT COMPANY (US) 1994-11-08 US disclosed
EP-0519485-A1 Propellant for gas generators Dynamit Nobel Aktiengesellschaft (DE) 1992-12-23 EP disclosed
US-5004742-A Enzyme inhibitors NIPPON HYPOX LABORATORIES INCORPORATED (JP) 1991-04-02 US disclosed
EP-0413051-A1 Benzothiazine-1,1-dioxide derivatives NIPPON HYPOX LABORATORIES INCORPORATED (JP) 1991-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 MEN1 2187/4885KMT2A 735/4885TAAR1 253/4885
US-20240368131-A1 OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF NLRP3, NLRP1, NOD1 MEN1 4618/4885KMT2A 4759/4885TAAR1 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.