SCHEMBL28367448

SCHEMBL28367448

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccccc1-c1cc(C#N)cc(-c2ccccc2-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.33
METAP2 P50579 1/20 0.33
ALDH1A3 P47895 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28372370 0.95 METAP2 (0.34) PIM1METAP2BCHEACHEGABRA1
SCHEMBL26529543 0.92 MAPKAPK2 (0.34) KDM4EHPGDPPARGNCOA2NCOA1
SCHEMBL28373388 0.92 PGR (0.37) METAP2ALDH1A3GABRA1GABRG2GABRB3
SCHEMBL28373332 0.89 SMYD2 (0.35) METAP2BCHEACHEGABRA1GABRG2
SCHEMBL28371419 0.89 TSPO (0.36) METAP2ALDH1A3KDM4EADORA2AALDH1A1
SCHEMBL26533808 0.87 GRM5 (0.39) PIM1METAP2ALDH1A3KDM4EHPGD
SCHEMBL18373940 0.87 GABRA1 (0.40) METAP2ALDH1A3BCHEACHEGABRA1
SCHEMBL26537689 0.87 PGR (0.37) METAP2ALDH1A3GABRA1GABRG2GABRB3
SCHEMBL28371604 0.86 KIF11 (0.40) ALDH1A1PGRDHODHMAPT
SCHEMBL28371601 0.85 ALDH1A1 (0.40) PIM1BCHEACHEALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914378-A Composition for use in organic light emitting diodes 九州有机光材股份有限公司 2020-03-24 CN disclosed