Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20580940 | 0.84 | GABRG2 (0.41) | DPP4NNMTSMN1; SMN2 | |
| SCHEMBL28375857 | 0.81 | MAOA (0.39) | HTTKDM4ELMNACYP3A4MAPT | |
| SCHEMBL28372514 | 0.76 | EHMT2 (0.50) | HTTKDM4EALDH1A1TSHR | |
| SCHEMBL28375855 | 0.73 | LMNA (0.36) | HTTKDM4ELMNACYP3A4MAPT | |
| SCHEMBL28373125 | 0.70 | CYP1A2 (0.38) | DPP4HTTKDM4ELMNACYP3A4 | |
| SCHEMBL28371735 | 0.69 | QDPR (0.34) | GAA | |
| SCHEMBL20581057 | 0.69 | GABRG2 (0.48) | DPP4KDM4ELMNACYP3A4MAPT | |
| SCHEMBL28885625 | 0.69 | KDM4E (0.38) | KDM4ELMNAMAPTAURKAGAA | |
| SCHEMBL20581869 | 0.68 | ERN1 (0.39) | HTTKDM4ELMNACYP3A4MAPT | |
| SCHEMBL22439223 | 0.68 | NNMT (0.42) | NNMTCYP3A4MAPTTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997671-A | Azaindole compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-04-10 | — | — | CN | disclosed |