Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791901 | 0.85 | MEN1 (0.55) | LTA4HOPRM1OPRK1HRH3MEN1 | |
| SCHEMBL12082512 | 0.85 | ALDH1A1 (0.56) | LTA4HOPRM1OPRK1HRH3MEN1 | |
| SCHEMBL27891330 | 0.83 | SIGMAR1 (0.63) | LTA4HOPRM1MEN1KMT2AACHE | |
| SCHEMBL3866505 | 0.83 | LTA4H (0.52) | LTA4HOPRM1OPRK1HRH3CYP2D6 | |
| SCHEMBL3158273 | 0.83 | LMNA (0.57) | LTA4HOPRM1OPRK1HRH3ALDH1A1 | |
| SCHEMBL1428200 | 0.83 | KDM4E (0.53) | LTA4HOPRM1OPRK1HRH3ALDH1A1 | |
| SCHEMBL8096431 | 0.83 | ACHE (0.66) | LTA4HOPRM1OPRK1HRH3MEN1 | |
| SCHEMBL28369901 | 0.83 | LTA4H (0.50) | LTA4HHRH3 | |
| SCHEMBL3750780 | 0.83 | HRH3 (0.45) | OPRM1OPRK1HRH3MEN1ALDH1A1 | |
| SCHEMBL15330514 | 0.83 | LTA4H (0.49) | LTA4HOPRM1OPRK1HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938076-B | Pyrrolopyrimidines as TLR7 agonists | 正大天晴药业集团股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-112898308-A | Pyrrolopyrimidines as TLR7 agonists | 正大天晴药业集团股份有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-110759916-B | Pyrrolopyrimidines as TLR7 agonists | 正大天晴药业集团股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-110938076-A | Pyrrolopyrimidines as TLR7 agonists | 正大天晴药业集团股份有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-110759916-A | Pyrrolopyrimidines as TLR7 agonists | 正大天晴药业集团股份有限公司 | 2020-02-07 | — | — | CN | disclosed |