SCHEMBL28376281

SCHEMBL28376281

CCC(C(=O)OC(C)(C)C)C(N)(O)O

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27578195 0.85 CTSS (0.36) NOS1NOS3NOS2CTSSCTSK
SCHEMBL27550061 0.85 CTSS (0.36) NOS1NOS3NOS2CTSSCTSK
SCHEMBL5154944 0.85 CTSK (0.35) NOS1NOS3NOS2CTSSCTSK
SCHEMBL15672769 0.81 CA1 (0.36) NOS1NOS3NOS2CTSSCTSK
SCHEMBL6116336 0.78 CYP2C9 (0.35) NOS1NOS3NOS2CTSSCTSK
SCHEMBL12470023 0.76 CTSK (0.38) CTSSCTSKCYP2C9CYP2C19LMNA
SCHEMBL13248625 0.74 NOS1 (0.32) NOS1NOS3NOS2
SCHEMBL3622799 0.74 CTSK (0.30) CTSKCYP2D6CYP2C9TSHRCYP2C19
SCHEMBL7081408 0.73 CTSS (0.40) CTSSCTSKCYP2C9CYP2C19KMT2A
SCHEMBL7435653 0.73 DGAT1 (0.44) CTSSCTSKLMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106750331-B High-adsorbability polyester material and preparation method thereof 东华大学 2020-08-11 CN claimed
CN-106750331-B High-adsorbability polyester material and preparation method thereof 东华大学 2020-08-11 CN disclosed
CN-107759779-B Antibacterial polyester material and preparation method thereof 东华大学 2020-04-07 CN disclosed