Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672769 | 0.74 | CA1 (0.36) | DGAT1USP2LMNACA1CA2 | |
| SCHEMBL28376281 | 0.73 | NOS1 (0.33) | LMNACA1CA2CTSSCTSK | |
| SCHEMBL30906944 | 0.71 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL6116336 | 0.71 | CYP2C9 (0.35) | DGAT1LMNACA1CA2CTSS | |
| SCHEMBL27578195 | 0.70 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL27550061 | 0.70 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL12470023 | 0.69 | CTSK (0.38) | LMNACA1CA2CTSSCTSK | |
| SCHEMBL8928053 | 0.67 | CA1 (0.42) | DGAT1USP2LMNACA1CA2 | |
| SCHEMBL4477961 | 0.67 | CA1 (0.42) | DGAT1CA1CA2CTSSCTSK | |
| SCHEMBL7081408 | 0.67 | CTSS (0.40) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180099-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066550-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |