Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699947 | 0.84 | LPL (0.38) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL10137263 | 0.80 | BCHE (0.39) | ENPP2 | |
| SCHEMBL723106 | 0.77 | ENPP2 (0.67) | ENPP2LPLLIPGTSHRF11 | |
| SCHEMBL331501 | 0.76 | TRPA1 (0.47) | TSHRALDH1A1TRPA1 | |
| SCHEMBL3781044 | 0.76 | ENPP2 (0.60) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL40256 | 0.74 | LPL (0.58) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL28378199 | 0.74 | ENPP2 (0.41) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL3791528 | 0.74 | LPL (0.58) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL806837 | 0.69 | ENPP2 (0.47) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL1229742 | 0.69 | ACHE (0.48) | ENPP2TSHRALDH1A1TRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | US | disclosed |
| US-8394357-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-12 | — | — | US | disclosed |
| US-7968714-B2 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2259061-A2 | Boronic acid derivatives | The Regents of The University of California (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-1960779-B1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | UNIV CALIFORNIA (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20090148344-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-02-12 | — | — | US | disclosed |
| US-6653141-B2 | In vitro detection of polyhydroxyl-substituted organic molecules; obtain sample, incubate in fluorescent dye exposure to excitation light detect and measure signal | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-25 | — | — | US | disclosed |
| US-6627177-B2 | Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002057273-A9 | SERINE PROTEASE INHIBITORS COMPRISING A HYDROGEN-BOND ACCEPTOR | TRIGEN LTD (GB) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020106326-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof | CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE | 2002-08-08 | — | — | US | disclosed |
| US-20020106810-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vitro method utilizing a boronic acid adduct and the device thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-08-08 | — | — | US | disclosed |
| WO-2002057273-A1 | SERINE PROTEASE INHIBITORS COMPRISING A HYDROGEN-BOND ACCEPTOR | TRIGEN LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | ENPP2 3653/4885LPL 3480/4885LIPG 1898/4885 |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, BLVRB, FOSB | ENPP2 3886/4885LPL 3358/4885LIPG 1681/4885 |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | ENPP2 3653/4885LPL 3480/4885LIPG 1898/4885 |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | ENPP2 3653/4885LPL 3480/4885LIPG 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.