⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127211 | 0.71 | LPL (0.33) | — | |
| SCHEMBL865150 | 0.67 | PGK1 (0.42) | — | |
| SCHEMBL3350229 | 0.67 | LOXL2 (0.39) | — | |
| SCHEMBL18436346 | 0.67 | TRPA1 (0.36) | — | |
| SCHEMBL20474576 | 0.67 | — | — | |
| SCHEMBL865148 | 0.67 | — | — | |
| SCHEMBL8993656 | 0.67 | ACHE (0.48) | — | |
| SCHEMBL3267429 | 0.67 | ACHE (0.48) | — | |
| SCHEMBL14264978 | 0.67 | PTGS2 (0.39) | — | |
| SCHEMBL13547712 | 0.65 | RAPGEF4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476383-B2 | Process for producing polyolefins | BOREALIS AG (AT) | 2013-07-02 | — | — | US | disclosed |
| EP-2330135-B1 | Process for producing polyolefins | BOREALIS AG (AT) | 2012-11-07 | — | — | EP | disclosed |
| US-20120178887-A1 | PROCESS FOR PRODUCING POLYOLEFINS | BOREALIS AG (AT) | 2012-07-12 | — | — | US | disclosed |
| WO-2011066892-A1 | PROCESS FOR PRODUCING POLYOLEFINS | BOREALIS AG (AT) | 2011-06-09 | — | — | WO | disclosed |
| EP-2330135-A1 | Process for producing polyolefins | Borealis AG (AT) | 2011-06-08 | — | — | EP | disclosed |