Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | CA9 | Q16790 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073756 | 0.96 | GAA (0.70) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL3317877 | 0.83 | CA2 (1.00) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL1732796 | 0.83 | GAA (1.00) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL29871288 | 0.83 | GAA (1.00) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL109925 | 0.83 | GAA (1.00) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL29363328 | 0.83 | GAA (1.00) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL156846 | 0.81 | ALDH1A1 (1.00) | GAAMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL28556898 | 0.81 | GAA (0.96) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL29939025 | 0.81 | ALDH1A1 (1.00) | GAAMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL9447766 | 0.81 | GAA (0.96) | GAAMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111048676-A | Perovskite luminescent layer, preparation method thereof, luminescent device and display device | 京东方科技集团股份有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-111048676-A | Perovskite luminescent layer, preparation method thereof, luminescent device and display device | 京东方科技集团股份有限公司 | 2020-04-21 | — | — | CN | disclosed |