Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28392426 | 0.90 | MAPT (0.40) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL28395385 | 0.87 | RECQL (0.35) | MAPTSMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL28398223 | 0.87 | MAPK14 (0.38) | MAPTSMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL28396598 | 0.87 | PTGS2 (0.46) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL28398492 | 0.87 | BCAT1 (0.38) | MAPTKMT2APOLBGAATDP1 | |
| SCHEMBL28392586 | 0.86 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL28397376 | 0.84 | GRM5 (0.35) | MAPTSMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL28405837 | 0.79 | RPA1 (0.35) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28400108 | 0.79 | KMT2A (0.39) | KMT2APOLBHTTPTGS2MAPK14 | |
| SCHEMBL28396599 | 0.78 | PTGS2 (0.44) | MAPTMEN1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |