Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405840 | 0.91 | RPA1 (0.36) | RPA1MGLLCNR2CNR1NPBWR1 | |
| SCHEMBL28395385 | 0.86 | RECQL (0.35) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL28398492 | 0.86 | BCAT1 (0.38) | MAPTKMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28400108 | 0.86 | KMT2A (0.39) | MGLLHTTKMT2AKCNJ6KCNJ5 | |
| SCHEMBL28392425 | 0.79 | MAPT (0.37) | MEN1NPC1MAPTHTTRAB9A | |
| SCHEMBL28396598 | 0.79 | PTGS2 (0.46) | MEN1NPC1MAPTHTTRAB9A | |
| SCHEMBL28398223 | 0.79 | MAPK14 (0.38) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL28392586 | 0.78 | ALDH1A1 (0.45) | MEN1NPC1MAPTHTTRAB9A | |
| SCHEMBL28395388 | 0.77 | RECQL (0.34) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL28398495 | 0.77 | GRM5 (0.38) | MAPTKMT2ASMN1; SMN2KCNJ6KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |