Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397377 | 0.91 | GRM5 (0.36) | GRM5PTGS2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28396598 | 0.86 | PTGS2 (0.46) | GRM5PTGS2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28398223 | 0.84 | MAPK14 (0.38) | PTGS2KCNJ6KCNJ5KCNJ3CYP2C9 | |
| SCHEMBL28395385 | 0.84 | RECQL (0.35) | PTGS2KCNJ6KCNJ5KCNJ3KDM1A | |
| SCHEMBL28392425 | 0.84 | MAPT (0.37) | PTGS2KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL28398492 | 0.84 | BCAT1 (0.38) | GRM5KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL28392586 | 0.83 | ALDH1A1 (0.45) | KCNJ6KCNJ3NPC1ALDH1A1MAPT | |
| SCHEMBL28395390 | 0.82 | GABRB3 (0.43) | SMN1; SMN2 | |
| SCHEMBL28400108 | 0.79 | KMT2A (0.39) | GRM5PTGS2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28396599 | 0.77 | PTGS2 (0.44) | GRM5PTGS2KCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |