Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396599 | 0.90 | PTGS2 (0.44) | PTGS2NR3C2MAPTMEN1KMT2A | |
| SCHEMBL28395385 | 0.87 | RECQL (0.35) | PTGS2MAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL28398223 | 0.87 | MAPK14 (0.38) | PTGS2MAPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28392425 | 0.87 | MAPT (0.37) | PTGS2MAPTMEN1KMT2AGAA | |
| SCHEMBL28398492 | 0.87 | BCAT1 (0.38) | MAPTKMT2AGAAKDM4EKCNJ6 | |
| SCHEMBL28400108 | 0.86 | KMT2A (0.39) | PTGS2KMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28397376 | 0.86 | GRM5 (0.35) | PTGS2MAPTKDM4EKCNJ6KCNJ5 | |
| SCHEMBL28392586 | 0.86 | ALDH1A1 (0.45) | MAPTMEN1KMT2AGAAKCNJ6 | |
| SCHEMBL28399294 | 0.80 | ALDH1A1 (0.33) | PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28405837 | 0.79 | RPA1 (0.35) | MAPTMEN1KMT2AKCNJ6KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |