SCHEMBL2839768

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2838267	0.83	ALDH1A1 (0.39)	ESR1ESR2NQO2ALDH1A1TSHR
	SCHEMBL15268291	0.79	KDM4E (0.49)	NQO2ALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL2237640	0.78	NQO2 (0.35)	ESR1ESR2NQO2ALDH1A1TSHR
	SCHEMBL2242688	0.76	IDO1 (0.42)	ESR2KDM4EKMT2ATDO2MEN1
	SCHEMBL2838373	0.76	MEN1 (0.39)	NQO2ALDH1A1TSHRKDM4EHSD17B10
	SCHEMBL2836126	0.76	TDO2 (0.46)	NQO2ALDH1A1L3MBTL1KDM4EKMT2A
	SCHEMBL2216607	0.75	NPC1 (0.40)	ALDH1A1KDM4EHPGDHSD17B10KMT2A
	SCHEMBL2216620	0.74	TDO2 (0.42)	ALDH1A1L3MBTL1KDM4EKMT2ATDO2
	SCHEMBL8087290	0.73	LMNA (0.47)	NQO2ALDH1A1TSHRL3MBTL1KDM4E
	SCHEMBL2213375	0.73	PDE1B (0.38)	ESR1ESR2NQO2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.