Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26252983 | 0.88 | CA2 (0.57) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL30938679 | 0.88 | CA2 (0.57) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28401134 | 0.85 | CA1 (0.46) | MAPTSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL30938684 | 0.85 | CA1 (0.46) | MAPTSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL28888736 | 0.85 | GRM5 (0.46) | MAPTSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL28398676 | 0.84 | PTGS2 (0.51) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28453359 | 0.84 | PTGS2 (0.51) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL22558313 | 0.84 | MAPT (0.56) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28406243 | 0.83 | KEAP1 (0.47) | MAPTSMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL28229562 | 0.82 | PTGS2 (0.57) | MAPTSMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170955-B | Green preparation method of 2H-1,2,3-triazole compound | 河南师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111170955-A | Green preparation method of 2H-1,2, 3-triazole compound | 河南师范大学 | 2020-05-19 | — | — | CN | disclosed |