Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401134 | 1.00 | CA1 (0.46) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL30938679 | 0.88 | CA2 (0.57) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL26252983 | 0.88 | CA2 (0.57) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL28888736 | 0.85 | GRM5 (0.46) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL28400475 | 0.85 | MAPT (0.46) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL28369719 | 0.84 | PTGS2 (0.53) | CA1CA2CA5ACA5BALDH1A1 | |
| SCHEMBL22558313 | 0.84 | MAPT (0.56) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL28406243 | 0.83 | KEAP1 (0.47) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL28229562 | 0.82 | PTGS2 (0.57) | CA1CA2CA5ACA5BMAPT | |
| SCHEMBL31469553 | 0.81 | CHRNB2 (0.44) | CA1CA2CA5ACA5BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184606-A | Method for preparing 2, 5-disubstituted and 2,3, 5-trisubstituted furan skeleton derivative | 中国医学科学院药物研究所 | 2024-06-14 | — | — | CN | disclosed |