Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26252983 | 1.00 | CA2 (0.57) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28888736 | 0.88 | GRM5 (0.46) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28400475 | 0.88 | MAPT (0.46) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28401134 | 0.88 | CA1 (0.46) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL30938684 | 0.88 | CA1 (0.46) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL22558313 | 0.87 | MAPT (0.56) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28406243 | 0.86 | KEAP1 (0.47) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28229562 | 0.86 | PTGS2 (0.57) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28395793 | 0.84 | CA1 (0.48) | CA2CA1CA5ACA5BMAPT | |
| SCHEMBL28559130 | 0.83 | CA2 (0.55) | CA2CA1CA5ACA5BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184606-A | Method for preparing 2, 5-disubstituted and 2,3, 5-trisubstituted furan skeleton derivative | 中国医学科学院药物研究所 | 2024-06-14 | — | — | CN | disclosed |